Scientific Research

The Studies Behind the Formula

As part of Dr. Pendleton's commitment to science-based wellness, our ingredients are chosen based on clinical research supporting their safety and effectiveness.

Bromelain for Oral Health: Antioxidant and Anti-Inflammatory Findings from a 2018 Lab Study

Published in 2018, this scientific paper evaluated purified bromelain from Ananas comosus (pineapple) using in vitro antioxidant assays and a labor...
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Quercetin, Rutin, Bromelain, and L-Carnosine for Borderline Uric Acid: What a 2020 Clinical Trial Found

Published in 2020, this scientific paper reports a 3-month, double-blind, randomized, placebo-controlled clinical trial evaluating Uricemin® (querc...
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Bromelain from Pineapple: Science-Backed Therapeutic Benefits and Mechanisms

Published on December 10, 2012, this scientific paper reviews bromelain, a pineapple-derived enzyme mixture, and summarizes reported biochemical pr...
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Quercetin for Kidney Disease? What a 2023 Commentary Really Says

This scientific paper comments on an earlier review about quercetin and kidney disease and argues that the evidence, while promising, is still frag...
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Quercetin and Ciprofloxacin: Rat Study on Kidney Oxidative Stress

This scientific paper examined whether quercetin could influence kidney injury and oxidative stress caused by the antibiotic ciprofloxacin in Wista...
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Quercetin and Kidney Health: What a 2022 Study Really Says

This scientific paper reviews how the natural flavonoid quercetin may support kidney health in many experimental models of injury, including toxici...
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Quercetin Dihydrate And Oxidative Stress: Mouse Study Summary

In a randomized controlled mouse study, the paper reports that quercetin dihydrate at 60 or 120 mg/kg body weight was linked with lower [malondiald...
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Quercetin And Uric Acid Levels: Human Trial Summary

In this controlled human trial, 500 mg of quercetin daily for 4 weeks was associated with a 7.8% reduction in plasma uric acid levels in healthy me...
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Potassium Citrate for Uric Acid Kidney Stones: Long-Term Study Summary

This scientific study followed 18 patients with uric acid kidney stones treated long-term with potassium citrate. The authors reported higher urine...
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Medical Management of Kidney Stones With Potassium Citrate Explained

This peer-reviewed scientific paper reviews how metabolic evaluation and targeted therapies are used in clinical practice for recurrent kidney ston...
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