Scientific Research

The Studies Behind the Formula

As part of Dr. Pendleton's commitment to science-based wellness, our ingredients are chosen based on clinical research supporting their safety and effectiveness.

Quercetin And Uric Acid Levels: Human Trial Summary

In this controlled human trial, 500 mg of quercetin daily for 4 weeks was associated with a 7.8% reduction in plasma uric acid levels in healthy me...
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Potassium Citrate for Uric Acid Kidney Stones: Long-Term Study Summary

This scientific study followed 18 patients with uric acid kidney stones treated long-term with potassium citrate. The authors reported higher urine...
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Medical Management of Kidney Stones With Potassium Citrate Explained

This peer-reviewed scientific paper reviews how metabolic evaluation and targeted therapies are used in clinical practice for recurrent kidney ston...
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Potassium Citrate for Medullary Sponge Kidney Stones: Long-Term Study Summary

This scientific paper reports that, in this cohort, long-term potassium citrate treatment was associated with a marked reduction in observed stone ...
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Does Potassium Citrate Affect Metabolism in Kidney Stone Patients?

This peer-reviewed study from the Swiss Kidney Stone Cohort examined how potassium citrate therapy affected urinary chemistry and metabolic markers...
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Can Potassium Citrate Help Small Kidney Stones?

This 2021 clinical study followed 56 patients with 86 kidney stones smaller than 10 millimeters who were treated with potassium citrate tablets for...
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Tart Cherry Citrate for Gout: What a 12-Week Trial Found

In this 12-week randomized trial of 282 men with gout and acidic urine starting febuxostat, tart cherry supplementary citrate mixture, citrate mixt...
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Can Tart Cherry Juice Affect Gout Flares? Inside a 12-Month Trial Protocol

This scientific paper describes a 12-month, double-blind, randomized controlled trial that will test whether daily Montmorency tart cherry juice mi...
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Tart Cherry Powder Effects on Uric Acid: A 2020 Rat Study Review

Does tart cherry powder help with high uric acid? A 2020 rat study found that a low dose might slightly lower uric acid levels and support kidney h...
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Tart Cherry Juice Reduces Uric Acid in Overweight Adults: A 2019 Study Review

Can tart cherry juice support joint health? A 2019 study found that drinking 100% tart cherry juice daily significantly lowered uric acid levels in...
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