Does Adderall Cause Kidney Stones? Guide to Safe Medication

Posted by Alerna Kidney Health on

  • Adderall is a prescription medication primarily used to treat ADHD but is often misused for weight loss or increased productivity.
  • Excessive use or misuse of Adderall can strain the kidneys through dehydration, high blood pressure, and other factors, but there isn't direct evidence linking it to kidney stones.
  • Safeguarding kidney health while taking Adderall involves staying hydrated, following the prescription, and maintaining a balanced diet.
  • If you have kidney stones or other kidney concerns and are considering taking Adderall, it's essential to consult your healthcare provider.
  • To prevent kidney stones, drink plenty of water, consume a balanced diet, reduce sodium intake, and consider natural supplements such as D-Mannose.
  • It is crucial to seek medical advice if you experience severe side effects from Adderall use, have existing kidney issues, or are concerned about the medication's impact on your kidney health.
Image of colorful pills.

Adderall, a widely used prescription medication, is primarily prescribed to treat attention deficit hyperactivity disorder (ADHD). Its effectiveness in increasing focus and concentration has led to its misuse by individuals seeking to boost their productivity or lose weight.1 While the potential benefits of Adderall may seem appealing, its impact on kidney health raises questions.

This article will explore the connection between Adderall use and kidney stones.2 We'll also examine the precautions one should take to safeguard their kidneys while using Adderall, including when it might be necessary to seek medical advice.

What is Adderall, and What Does It Do?

Adderall is a prescription medication that contains two active ingredients: amphetamine and dextroamphetamine.3 These are both stimulant medications that affect the brain's neurotransmitters, increasing the levels of dopamine and norepinephrine. By doing so, Adderall helps improve focus, attention, and impulse control, making it an effective treatment for Attention Deficit Hyperactivity Disorder (ADHD).

Adderall primarily manages ADHD symptoms, including inattention, hyperactivity, and impulsivity. However, it has also found off-label use in treating narcolepsy, a sleep disorder characterized by excessive daytime sleepiness. When taken as prescribed, Adderall can significantly improve the quality of life for individuals with these conditions.

Who Takes Adderall and Why?

Adderall is mainly prescribed to individuals diagnosed with ADHD, including children, adolescents, and adults. ADHD is a neurodevelopmental disorder that can cause difficulties with concentration, organization, and impulse control.13 Adderall helps alleviate these symptoms, enabling those with ADHD to function better in various aspects of their lives, including school, work, and social situations.

Unfortunately, Adderall's stimulant properties have made it a popular drug for misuse, particularly among college students and young adults. Some use it as a "study drug" to enhance concentration and focus during long study sessions. Others misuse it for recreational purposes or as a weight-loss aid, as it can suppress appetite.411

It's important to note that using Adderall without a prescription or in ways other than prescribed can be dangerous and lead to adverse effects.

Are they more prone to Kidney Stones?

There is no direct evidence that Adderall users are more prone to kidney stones. However, the misuse or abuse of Adderall can negatively affect overall health, including the kidneys.25

Chronic misuse may lead to dehydration, which is a risk factor for kidney stones. Dehydration reduces urine volume, allowing minerals and salts to accumulate and form kidney stones more easily.

In addition, some individuals taking Adderall may experience appetite suppression, leading to inadequate nutrition and potential malnutrition. This could negatively impact kidney function and increase the risk of kidney stones. Individuals taking Adderall must maintain proper hydration and nourishment to support kidney health.

Does Adderall Cause Kidney Stones?

Adderall, when used as prescribed, is not known to cause kidney stones directly. However, certain factors associated with Adderall use or misuse may indirectly increase the risk of kidney stones. These factors include dehydration, poor nutrition, and the strain on the kidneys from processing the drug.257 It's essential for individuals taking Adderall to follow their healthcare professional's recommendations, stay hydrated, and consume a balanced diet to minimize the risk of kidney stones.

Kidney stones can develop due to various factors, including genetics, diet, hydration status, and overall health. Therefore, while there is no direct link between Adderall and kidney stones, it is crucial to consider individual risk factors and make healthy lifestyle choices to protect kidney health.

Effects of Adderall Misuse on Other Organs

Abuse of Adderall can have wide-ranging effects on various organs in the body.3 Here are some of the potential consequences:

  1. Heart and Circulatory System: The stimulant nature of Adderall can increase heart rate and blood pressure, which can strain the heart and blood vessels over time. This can potentially lead to cardiovascular issues such as heart attack, stroke, or arrhythmias.
  2. Nervous System: Chronic misuse of Adderall can impact the brain and nervous system. It may increase the risk of mental health disorders such as depression, anxiety, and psychosis.
  3. Digestive System: Long-term Adderall misuse can suppress appetite, potentially leading to malnutrition and unhealthy weight loss. It may also cause gastrointestinal issues such as nausea, vomiting, and diarrhea.
  4. Liver and Metabolic System: Prolonged abuse of Adderall can burden the liver,6 potentially leading to liver damage or failure. It may also impact the body's metabolic processes.
  5. Immune System: Adderall misuse can weaken the immune system, increasing susceptibility to infections and diseases.

It is crucial to note that the risks and severity of these effects may vary depending on individual factors such as age, health conditions, dosage, and duration of misuse.

Safeguarding Your Kidneys While Taking Adderall

If you are taking Adderall as prescribed by a healthcare professional, following the recommended dosage and avoiding misuse is essential.89 Here are some tips to safeguard your kidneys while taking Adderall:

  1. Stay Hydrated: Drink plenty of water to help flush toxins out of your kidneys and prevent kidney stones.
  2. Eat a Balanced Diet: Proper nutrition, including kidney function, is essential for overall health. Consume a balanced diet rich in fruits, vegetables, whole grains, and lean protein.
  3. Monitor Blood Pressure: Since Adderall can increase blood pressure, regularly monitor your blood pressure levels and follow your healthcare professional's recommendations to manage it.
  4. Avoid Dehydration: Avoid excessive caffeine or alcohol intake, which can contribute to dehydration and kidney strain.
  5. Consult Your Healthcare Professional: If you have pre-existing kidney conditions or are at high risk of kidney stones, consult your healthcare professional for specific recommendations regarding Adderall use.

Tips for Taking Adderall Safely

Whether you're using Adderall for ADHD or another medical condition, several tips ensure you're using the medication as securely and effectively as possible.12

  1. Follow Prescription Guidelines: Always take Adderall as prescribed by your healthcare professional. Please do not increase the dosage or frequency without consulting them.
  2. Communicate with Your Healthcare Professional: Inform your healthcare professional about any pre-existing health conditions, medications, or supplements you are taking to avoid potential interactions or complications.
  3. Avoid Misuse: Do not use Adderall recreationally or for non-medical purposes. Misuse can increase the risk of adverse effects on the kidneys and other organs.
  4. Monitor for Side Effects: Be aware of any side effects or changes in your physical or mental health while taking Adderall. Report any unusual symptoms to your healthcare professional.
  5. Prioritize Self-Care: Engage in healthy lifestyle practices such as regular exercise, stress management, and adequate sleep to support overall well-being and kidney health.

Can I Still Take Adderall If I Have Kidney Stones?

If you have kidney stones or a history of kidney stones, it is essential to consult your healthcare professional before taking Adderall. They will assess your overall health, risk factors, and specific needs to determine the most appropriate treatment plan.

Ways to Prevent Kidney Stones

Kidney stones can be painful and uncomfortable, leading to more severe complications if not managed properly. The good news is that there are several ways to reduce your risk of developing kidney stones through simple lifestyle changes and dietary adjustments.89

  1. Stay Hydrated: Drink plenty of water throughout the day to help flush out toxins and prevent the formation of kidney stones.
  2. Limit Oxalate-Rich Foods: If you are prone to kidney stones, consider limiting your intake of oxalate-rich foods such as spinach, beets, and nuts.
  3. Moderate Animal Protein Intake: Reduce excessive consumption of animal protein, which can increase the risk of kidney stones.
  4. Consume a Balanced Diet: Prioritize a balanced diet with adequate calcium, potassium, and magnesium to support kidney health.
  5. D-Mannose: This natural sugar is found in some fruits and can help prevent certain kidney stones by inhibiting the adhesion of bacteria to the urinary tract lining.10

When to Seek Medical Advice?

If you're taking Adderall and are experiencing any unusual symptoms or side effects, it's essential to consult your healthcare professional. While Adderall can be an effective medication for certain conditions, improper use can lead to kidney issues or exacerbate existing health problems.

If you already have kidney stones or are prone to developing them, discussing your medication options and dosages with your doctor is essential. They may recommend alternative treatments or lifestyle changes to reduce the risk of kidney stone formation. Regular monitoring of your kidney function may also be advised.

Furthermore, if you're considering taking Adderall, whether for a legitimate medical condition or other purposes, you should consult a healthcare provider first. They can help determine the appropriate dosage and frequency of use, considering your specific medical history and needs.

Remember, any decision involving medication should always be made in consultation with a qualified healthcare professional. It's crucial to prioritize your health and well-being, especially when dealing with prescription medications like Adderall that can significantly affect your body.

Take Control of Your Urinary Health - Start with D-Mannose Today


Adderall is a prescription medication used to treat ADHD. While there is no direct link between Adderall and kidney stones, its misuse may increase the risk of kidney strain or damage. Safeguarding your kidneys while taking Adderall involves following prescription guidelines, staying hydrated, and maintaining a balanced diet.

It is essential to prioritize kidney health and seek medical advice if you have concerns about kidney stones or Adderall use. Remember, taking care of your kidneys is vital for overall health and well-being. Take care of your kidneys, Incorporate D-Mannose into Your Daily Wellness Routine.

Frequently Asked Questions:


There is currently no direct scientific evidence that links Adderall use with the development of kidney stones. Excessive or misuse of Adderall can have adverse effects on kidney health, including increased blood pressure and dehydration, which can contribute to the formation of kidney stones.


Adderall's long-term misuse can strain or damage the kidneys, potentially leading to kidney disease or other kidney problems. This strain or damage can result from several factors associated with Adderall misuse, such as dehydration from reduced fluid intake, increased blood pressure from stimulant effects, and reduced kidney blood flow due to vasoconstriction. All these factors can ultimately contribute to kidney stress and potential damage.


If you already have kidney stones, it is crucial to consult your healthcare provider before taking Adderall. Your medical history and current condition are essential considerations in determining whether Adderall is appropriate for you. Taking Adderall without proper medical guidance can further aggravate existing kidney problems or contribute to other health issues.


To reduce the risk of developing kidney stones while taking Adderall, it is important to stay hydrated, follow your prescription dosage instructions, and maintain a balanced diet rich in fruits, vegetables, and whole grains.

Medical Disclaimer:

The information provided in this article is for educational and informational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Please consult with your healthcare provider before starting any new dietary supplement, especially if you are pregnant, nursing, have a medical condition, or are taking other medications. Never disregard professional medical advice or delay in seeking it because of something you have read in this article.


  1. Adderall Side Effects, Risks & Dangers of Use. (n.d.). American Addiction Centers. Accessed 22 August 2023.
  2. Mansoor K, Kheetan M, Shahnawaz S, Shapiro AP, Patton-Tackett E, Dial L, Rankin G, Santhanam P, Tzamaloukas AH, Nadasdy T, Shapiro JI, Khitan ZJ. Systematic review of nephrotoxicity of drugs of abuse, 2005-2016. BMC Nephrol. 2017 Dec 29;18(1):379. doi: 10.1186/s12882-017-0794-0. PMID: 29287591; PMCID: PMC5747941.
  3. Adderall Side Effects & Signs of Abuse | Side Effects of Adderall. (n.d.). The Recovery Village Drug and Alcohol Rehab. Accessed 22 August 2023.
  4. Adderall Abuse and Addiction: Symptoms, Statistics, and More. (n.d.). The Recovery Village Drug and Alcohol Rehab. Accessed 22 August 2023.
  5. Effects of Substance Abuse on the Renal System (Kidneys). (n.d.). American Addiction Centers. Accessed 22 August 2023.
  6. Stimulants: Toxic to Kidneys and Liver. (n.d.). Narconon International. Accessed 22 August 2023.
  7. Foley, R. J., Kapatkin, K., Verani, R., & Weinman, E. J. (1984). Amphetamine-induced acute renal failure. Southern medical journal77(2), 258–260.
  8. Kidney stones - Prevention. Accessed 22 August 2023.
  9. How to prevent kidney stones - Harvard Health. (2013, October 4). Harvard Health. Accessed 22 August 2023.
  10. Cooper, T. E., Teng, C., Howell, M., Teixeira-Pinto, A., Jaure, A., & Wong, G. (2022). D-mannose for preventing and treating urinary tract infections. The Cochrane database of systematic reviews8(8), CD013608.
  11. Adderall Addiction And Abuse. (n.d.). Addiction Center. Accessed 22 August 2023.
  12. Adderall: 7 things you should know - (n.d.). Accessed 22 August 2023.

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